Best Price Acanthopanax Senticosus Extract

• CAS No.: 7374-79-0
• Formula: C28h36o13
• EINECS: /
• Resource: Acanthopanax Senticosus Extract
• Sample Order: Acceptable
• Test Method: HPLC
• Model NO.: IB0037
• Cultivation Method: Artificial Planting
• Model Number: 1%-98%
• Package: 1kg/Bag 25kg/Drum
• Transport Package: 25kg/Drum
• Specification: 1%-98%
• Trademark: Innovy
• Origin: China
• HS Code: 1302199099
• Production Capacity: 1000000000000

Product Description

Product Description

 


 

What's Acanthopanax senticosus extract?

Acanthopanax senticosus is distributed in Heilongjiang, Jilin, Liaoning, Hebei and Shanxi of China. Born in hillside forests and roadside shrubs; Medicine beds are often cultivated. Root skin dispels rheumatism and strengthens muscles and bones. Make Wujiapi wine (or Wujiapi powder) with wine. The root bark contains volatile oil, tannin, palmitic acid, linoleic acid, vitamin A and B1. The root bark can also replace the "bark of Acanthopanax senticosus" for healthcare purposes; Seeds can be used to extract oil and make soap.

 

Acanthopanax senticosus extract is an effective ingredient extracted from the Acanthopanax senticosus plant of the Araliaceae family. It has the effects of invigorating qi, invigorating the spleen, tonifying the kidney and soothing the nerves.

 

  

Product Name	Acanthopanax senticosus extract
Appearance	Brown yellow powder
Specification	10:1 20:1 50:1  0.8%
Active ingredient	Eleutheroside B ,E
Particle size	80 mesh
Test Method	HPLC
MOQ	1KG
Package	1Kg/Foil bag,25Kg/Drum
Delivery Time	5-10 Working Days
Shelf Time	2 year

 


 

 

Application

Application of Acanthopanax Extract

Echinacoside is the main active ingredient of Erythrina officinalis, Erythrina glycosides are mainly distributed in the root and stem of Erythrina officinalis, which have various effective effects on the human body.

1. Effects on cardiovascular system
There are many reports in the literature on the protection of cardiovascular and cerebral blood vessels, the main chemical components play a role in the saponins, studies have shown that acanthopanax glycosides improve the phenomenon of cerebral ischemia, may be related to its significant improvement of microcirculation, increase the blood supply to the brain tissue; at the same time, acanthopanax glycosides can also improve the phenomenon of myocardial ischemia and myocardial ischemia caused by the damage.
Sui-Da-Mian et al. found that acanthopanax glycosides can improve the arrhythmia caused by myocardial ischemia/reperfusion (IRI) in rats by enhancing the activity of antioxidant enzymes in myocardial tissues, decreasing free radicals and Ca2+ overload, and can significantly reduce the area of myocardial infarction caused by myocardial ischemia/reperfusion as well as the content of lipid peroxides in the serum and liver tissues in hyperlipidaemic rats, and also inhibit the aggregation of platelets and improve the blood rheology of the rats in the acute haematochezia model. It also inhibited platelet aggregation, improved the abnormal changes of blood rheology in rats with acute blood stasis model, played the role of anti-atherosclerosis and prevented the formation of thrombus and myocardial infarction, so the protective effect of myocardial ischemia may be related to the improvement of its haemodynamics.
In addition, Sentoside B can significantly increase the left ventricular systolic blood pressure (LVSP), (systolic blood pressure) SBP, reduce LVEDP, acute myocardial infarction rats, acute myocardial infarction rats play a protective role, may be its enhancement of antioxidant enzyme activity, reduce free radicals damage, to correct the metabolic disorders of (free fatty acid) FFA and (lactic acid) LA accumulation, inhibit inflammatory reactions and other mechanisms related to, and has a Resistance to hydrogen peroxide-induced cardiomyocyte damage in lactating rats and myocardial ischaemia-reperfusion injury in rats, and suggests that it should have antioxidant activity.

2. Hypoglycaemic effect
Sentineloside in vivo can reduce the blood glucose level of dependent diabetes mellitus (NIDDM) rat model after 30 min of fasting and oral glucose, and increase the level of glucagon-like peptide (GLP-1),  C-peptide, and increase the secretion of type 2 diabetes mellitus rats, and  β-cells, but has no effect on the normal rats;. At the same time, some studies have shown that acanthoside (ASS) can reduce the blood glucose level in experimental diabetes mellitus rats, increase the plasma and pancreatic lipid peroxide (LPO) content and superoxide dismutase activity, and improve the activity of anti-oxidative enzymes and anti-peroxidative damage has a close relationship.

3.Anti-tumour effects
By inhibiting the mitosis of hepatocellular carcinoma cells (HepG-2) and the synthesis of deoxyribonucleic acid (DNA), it prevents the proliferation of hepatocellular carcinoma cells and promotes the apoptosis of hepatocellular carcinoma cells. Accelerates apoptosis of lung cancer cells by affecting protein expression in lung cancer cells (Spc-A1), altering lung cancer cell morphology and cycle dynamics. It can inhibit the synthesis of deoxyribonucleic acid (DNA) in gastric cancer cells (SGC-7901) and slow down the proliferation of gastric cancer cells by promoting the inward flow of Ca2+.
The related research shows that the mechanism of tumour inhibition of acanthopanax glycosides may be related to its role in controlling the expression of related genes and proteins, that is, inhibit the expression of Bcl-2 protein, and promote the expression of Bax protein.

4. Sleeping aid
Since ancient times, it has been regarded as a tonic for prolonging life, traditional Chinese medicine believes that it has the effect of benefiting qi, strengthening the spleen, tonifying the kidneys and tranquilising the mind, and it is mainly used for spleen and kidney yang deficiency, weakness and fatigue, loss of appetite, lumbar and knee pain, dreaming and other illnesses. Han Dynasty "Shen Nong Ben Cao Jing" has long been listed as a "tonic, beneficial" role of the top quality medicine; "would rather get a handful of Wuga, not a car full of gold and jade", the Ming Dynasty Li Shizhen in the "Materia Medica Compendium" in the medical book of the spiny Wuga gave high praise; according to the "Practical Nourishing According to the "Practical Nutritional Chinese Medicine" book records, the prickly five plus has the benefit of qi and spleen, tonifying the kidneys and tranquillising the efficacy of the spirit, mainly used for spleen and kidney yang deficiency, fatigue, insomnia and dreaming and other conditions.
With the effect of benefiting qi and strengthening the spleen, tonifying the kidneys and calming the mind, Sophora Radix has the ability to improve the blood supply to the brain and produce a bidirectional regulation of excitation or inhibition to the central nervous system, which is conducive to the restoration of sleep and the adjustment of the cycle.   the reason why insomnia is because of excessive thinking, damage to the heart and spleen, deficiency of qi and blood or the heart and spirit of the onset of the loss of nutrients, prickly five plus has a tonic qi and blood, adjust the yin and yang, spleen and tranquillise the role of the spirit.

5. Enhance immunity
Acanthopanax can significantly increase the ability of cells to produce induced interferon, and has a protective effect on leucopenia caused by subcutaneous injection of cyclophosphamide, and also has a significant preventive effect on leucopenia. Acanthopanax showed significant improvement in hepatotoxicity and promoted the body's ability to resist infection against tuberculosis infection. Extracts of Acanthopanax were shown to stimulate cellular immunity. Therefore, Acanthopanax is used in a variety of immune-related diseases.

 

 

COA

 

Items	Standards	Results
Physical Analysis
Appearance	Fine Powder	Conforms
Color	brown yellow powder	Conforms
Odor	Characteristic	Conforms
Mesh Size	100% through 80% mesh size	Conforms
General Analysis
Identification	Identical to R.S. sample	Conforms
BE	≥0.8%	0.85%
Extract Solvents	Water	Conforms
Loss on Drying (g/100g)	≤5.0	2.23%
Ash(g/100g)	≤5.0	2.52%
Chemical Analysis
Pesticides Residue (mg/kg)	0.05	Conforms
Residual Solvent	<0.05%	Conforms
Residual Radiation	Negative	Conforms
Lead(Pb) (mg/kg)	<3.0	Conforms
Arsenic(As) (mg/kg)	<2.0	Conforms
Cadmium(Cd) (mg/kg)	<1.0	Conforms
Mercury(Hg) (mg/kg)	<0.1	Conforms
Microbiological Analysis
Total Plate Count(cfu/g)	≤1,000	300
Molds and Yeast (cfu/g)	≤100	30
Coliforms (cfu/g)	Negative	Conforms
Salmonella(/25g)	Negative	Conforms

 

 

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